What I usually use is this combination: Yoshi/Egg1/Roller (sometimes Wooden)/Super Glider, Gold Glider, or Paraglider. Like the above poster, great acceleration and handling.
I almost always use Yoshi or Daisy/ Egg 1/ Wood/ Gold Glider. Yeah, I prefer acceleration and handling in Mario Kart. I used to balance it with B-Dasher and Wood but not anymore.
For aces, they would select Egg 1, Roller wheels and Paraglider. But a lightweight character (i.e. Yoshi, Toad, Shy Guy) is required for the maximum performance.
I almost always use the Blue Seven/Bumble-V, Slick tires, and the Super Glider on the Grand Prix, however, I'll switch to the Red Monsters on off road courses like Kalimari Desert and DK Pass and online, as which courses are selected will be unpredictable. Sometimes on the Time Trials, I'll just look at the guide for inspiration.